Thursday, 30 April 2009

Tips for Those New to Low Dose Naltrexone (LDN)

Why you may get increased symptoms in 1st 3 months on LDN, by Dr. Bob Lawrence - http://preview. ca2flq

Why some May have problems with or fail LDN -
http://preview. dfv5ou

For those having trouble w/LDN no longer working -
http://preview. chajp3

Check yourself for
Candida (Yeast overgrowth) - http://preview. c9eyzx

Tests to check for
Candida yeast by Dr. McCandless - http://preview. cxp6bx

Wednesday, 29 April 2009

Low Dose Naltrexone (LDN) Prescription Guidelines for Doctors

Prescribing Low Dose Naltrexone – A Guide

Prescribing Low Dose Naltrexone – A Guide

Dr Tom Gilhooly Essential Health Clinic Glasgow"

You and Yours BBC Radio 4

An email was sent to You and Yours, BBC Radio 4 to suggest a programme on Low Dose Naltrexone (LDN). The response is below.
If you would like to contact the programme to suggest an item on LDN, please do so by following the link -

"Dear Bob,

Many thanks for your message.

We are aware of LDN and may consider doing a piece on it at
some point. I would therefore like to keep your details if
we need to contact you in the future.
Thank you again for contacting You and Yours.

Best wishes,
Carolyn Atkinson.
You and Yours"

ITV This Morning Item on LDN

Dr Tom Gilhooley is an expert on MS and a keen advocate of a revolutionary new treatment, LDN.

"This is a cheap drug and has been proved to be safe and, in my experience, very effective in treating MS. Any GP can prescribe it to patients with MS now if they wanted to, and patients can ask for it, but there's no guarantee that their GPs will want to give them it without a trial to prove its effectiveness."

Video Interviews from EU Low Dose Naltrexone (LDN) Conference, Glasgow 2009

Video interviews with various presenters, doctors and patients who were at the European Low Dose Naltrexone Conference in Glasgow, Scotland in April 2009.

Pre-registration for EU LDN Conference 2010 Available Now

You can now pre-register to attend the European Low Dose Nalrtrexone (LDN) Conference in Glasgow, Scotland, UK on Friday 23rd and Saturday 24th (Open to public on Saturday, clinicians only on Friday).

Dr Tom Gilhooly on ITV This Morning Programme 10:30 Wed 29th April 2009

Dr. Tom Gilhooly is appearing with TV doctor, Dr. Chris Steele on ITV's This Morning programme at 10:30 today, Wednesday 29th April 2009.

Video link will be posted here when it's available.

This is a great opportunity to tell 100's of thousands of viewers about Low Dose Naltrexone (LDN).

Tuesday, 28 April 2009

A Case of Remission from Crohn's Disease with Low Dose Naltrexone LDN

A Case of Remission from Crohn's Disease
with Low Dose Naltrexone LDN by Jeffrey Dach MD

Chronic Fatigue Sufferer Benefits from LDN

""Chronic fatigue syndrome drags you down," she said. "I'm now able to do things again. LDN has had a positive effect on me."" Coverage of European LDN Conference

Coverage including Mary Boyle's Bradley's radio show.

(Mary Boyle Bradley wrote a book on her experience with MS and LDN : Up the Creek with a Paddle, Beat MS and All Autoimmune Disorders with Low Dose Naltrexone (LDN) )

40 Year MS Patient Says LDN Works

40 Year MS Patient Says LDN Works

"Goldberg, who lives in Totteridge, North London, also tells me that he has just started to take low-dose Naltrexone, a drug used to treat addictions, which is gaining credibility as a treatment for MS. Its use in this context is not licenced in the UK and is supported only by small pilot clinical trials. “I know it works because I'm using it,” he says. “You could say it's a calculated experiment.”"

MS Patient's Journal on Her Experience with Low Dose Naltrexone (LDN)

MS Patient's Journal on Her Experience with Low Dose Naltrexone (LDN)

Julie Stachowiak, Ph.D., writes in of her experience using Low Dose Naltrexone (LDN) to treat her Multiple Sclerosis (MS)

Sunday, 26 April 2009

LDN and Fibromyalgia

LDN Helps Ease Symptoms of Fibromyalgia in Stanford U Pilot

Article - web site.

European LDN Conference 2009, Glasgow - Joseph Wouk's Talk on LDN

European LDN Conference 2009, Glasgow - Joseph Wouk's Talk on LDN

Joseph Wouk suffers from, or should I say, used to suffer from progressive, relapsing multiple sclerosis. Here he talks about his experiences with MS and his subsequent treatment and vast improvement on Low Dose Naltrexone (LDN)

European LDN Conference 2009, Glasgow, LDN Research Summary - Dr Tom Gilhooly, Essential Health Clinic, Glasgow

European LDN Conference 2009, Glasgow, LDN Research Summary - Dr Tom Gilhooly,

Essential Health Clinic, Glasgow

Although Low Dose Naltrexone (LDN) is just 1/50th of the standard dose of Naltrexone, a 30 year old drug with a good safety record, published research and science research is needed in order for UK NHS GPs and NHS clinicials in general to feel comfortable with prescribing LDN.

Summary of research -

Initial notable research - Penn State - A human study on Crohn's Disease patients showed great results. NOTE - With much larger doses than Dr T G is using.

Today - Dr Tom Gilhooly says we are 9 10ths of the way towards funding for the first trial in UK using LDN on Multiple Sclerosis (MS) patients (120 patients).

The patent protection for Naltrexone is long gone - So, it is unlikely there will be any studies carried out by any pharmaceutical company.

Therefore, University or - Charity funding is required

Hopefully government science funding in the UK will be available.

Again - Publication is required (Hence clinical use in Dr T G's clinic has not been written up - Not seen as relevant by most professionals)

Issue : Institutional resistance - Charities are wary of LDN

Accredited Funding needed - There is only 1 such MS charity, but they are not keen on LDN

Most research has concentrate on relatively large doses of 3 - 4 mg - Dr T G's clinic stat on 1mg and work up to optimum dose which is often not much more than 1 or even use 1mg -Therefore there is a need to educate researchers on dosage.

Short duration studies - 2 - 4 years needed for LDN. For use in cancer, 5 years - therefore more longer studies are more expensive, so need shorter cheaper studies with demonstrable results.

LDN in Cancer , MS - Dr Ian Zagon - Has been publishing results for 28 yrs. Has done multiple studies in animals (244 publications)

First in 1981 - Nalexone and cancer in mice.

Subsequently Dr Bernard Bihari became interested. He did lots of work but often unpublished. His work on HIV was refused publication by many journals so went unpublished.

Dr Ian Zagon - Found that opiate growth factor was increased by LDN and this seemed to naturally inhibit tumour growth in animals.

Used Experimental Allergic Encephalomyelitis (EAE) - This was induced in animals and treated wtih LDN

MS Society of America has funded research into this which will be published soon.

Dr I Z's MS study was presented at the September 2008 Montreal World Congress on MS.

Finding - High dose Naltrexone worsens EAE and makes humans feel worse.

Therefore, low dosages required and it is important to take once per day - So the effect us for a short duration.

Human Studies :

Fibromyalgia (FM) - Paper published last week.

There are 250,000 FM sufferers in the UK alone

Stanford - 10 FM patient study due to report in 2010.

Dr T G - Essential Health Clinic, Glasgow - Clinical findings -

Have been using LDN with FM for 6 months, much better than previous treatment - 80% improvement vs 20% with other approaches, e.g. Nutrition, lifestyle improvement.

Effect is very dosage dependant.

All studies used 4.5mg, TG - mostly 1 - 2 some people have trouble taking more than 1.

Penn State, Crohn's - Still the most impressive result.

Done by Professor Jill Smith, Penn State University.

17 patients over 12 weeks pilot study- Used 4.5 mg LDN (Again, note this is high compared with Dr T G's clinical experience).

Very rigourous - Close examination of colon.

Findings -

67% of patients went into remission.

89% responded positively in some way.

Dr T G's, EHC clinical findings - 3 patients , 2 with severe Crohn's - both entered remission with 1mg quite quickly. (NOTE - I am the 4th patient but I'm new! LOL)

One of Dr T G's NHS patients had bloody diarrhea so severe they had to have a blood transfusion. This patient is now in remission for over a year. The patient has actually stopped LDN as they didn't like to take drugs (!) but has maintained remission.

IBS Study- Kariv et al, Tel Aviv - 47 patients with 0.5mg (Very low dose) - Saw 76% improvement and increase in reduction in pain-free days.

Another study - 600 patients double-blind, randomised -

0.5 mg (Called PTI 901)

2 months of improvement, but no further improvement after 3 months.

Seems like too low a dose, so IBS not proven really.

Seifrabei et al AJAS 2008 - Study on Haematological cancers

5 months treatment with 3mg

Significant improvement in quality of life measurements at 1, 3 and 5 months follow up.

MS Study - Gironi et al Milan 2008

Dr T G's EHC Clinical experience - LDN is the best MS treatment.

Treated 40 primary progressive MS patients (Worst case scenario) over 6 months

Only 1 patient out of the 40 experienced any progression in their symptoms.

There was a significant reduction in spasticity found.

Cree et al - University of California at San Francisco

80 patients for 8 weeks, randomised controller trial using 4.5 mg

Significant improvement using MS Quality of Life Index.

Pain, mental health and cognition all improved significantly.

NOTE - Side Effects - No major adverse effects have been found in any of the studies done so far anywhere.

Therefore - There is no risk in prescribing LDN.

In Summary :

There have been numerous publications of results of using LDN.

LDN has been tested in use for a diverse range of medical conditions

LDN Seems to be useful for many conditions involving the immune system

Further Reading :

Dr Bihari -

Dr Ian Zagon -